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单选题
We must begin testing the instrument no matter _____ difficult it is.
A
what
B
when
C
how
D
however
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参考解析
解析：
句意：不论有多难，我们必须开始测验仪器。no matter how difficult相当于however it is difficult。
句意：不论有多难，我们必须开始测验仪器。no matter how difficult相当于however it is difficult。
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