考情前瞻:2021年考研英语医学类阅读理解模拟题及答案(六)

发布时间:2020-10-11


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At 18 Ashanthi DeSilva of suburban Cleveland is a living symbol of one of the great intellectual achievements of the 20th century. Born with an extremely rare and usually fatal disorder that left her without a functioning immune system (the bubble-boy disease,” named after an earlier victim who was kept alive for years in a sterile plastic tent) she was treated beginning in 1990 with a revolutionary new therapy that sought to correct the defect at its very source in the genes of her white blood cells. It worked. Although her last gene-therapy treatment was in 1992 she is completely healthy with normal immune function according to one of the doctors who treated her W. French Anderson of the University of Southern California. Researchers have long dreamed of treating diseases from hemophilia to cancer by replacing mutant genes with normal ones. And the dreaming may continue for decades more. There will be a gene-based treatment for essentially every disease,” Anderson says, “within 50 years.

It\'s not entirely clear why medicine has been so slow to build on Anderson\'s early success. The National Institutes of Health budget office estimates it will spend $432 million on gene-therapy research in 2005 and there is no shortage of promising leads. The therapeutic genes are usually delivered through viruses that don\'t cause human disease. The virus is sort of like a Trojan horse,” says Ronald Crystal of New York Presbyterian/Weill Cornell Medical College. The cargo is the gene.

At the University of Pennsylvania\'s Abramson Cancer Center immunologist Carl June recently treated HIV patients with a gene intended to help their cells resist the infection. At Cornell University researchers are pursuing gene-based therapies for Parkinson\'s disease and a rare hereditary disorder that destroys children\'s brain cells. At Stanford University and the Children\'s Hospital of Philadelphia researchers are trying to figure out how to help patients with hemophilia who today must inject themselves with expensive clotting drugs for life. Animal experiments have shown great promise.

But somehow things get lost in the translation from laboratory to patient. In human trials of the hemophilia treatment patients show a response at first but it fades over time. And the field has still not recovered from the setback it suffered in 1999 when Jesse Gelsinger an 18-year-old with a rare metabolic disorder died after receiving an experimental gene therapy at the University of Pennsylvania. Some experts worry that the field will be tarnished further if the next people to benefit are not patients but athletes seeking an edge. This summer researchers at the Salk Institute in San Diego said they had created a marathon mouse by implanting a gene that enhances running ability; already officials at the World Anti-Doping Agency are preparing to test athletes for signs of gene doping. But the principle is the same whether you\'re trying to help a healthy runner run faster or allow a muscular-dystrophy patient to walk. Everybody recognizes that gene therapy is a very good idea,” says Crystal. And eventually it\'s going to work.

(1):本文选自Newsweek;12/6/2004 p55-55 2/3p 1c;

(2):本文习题命题模仿对象: 第12题分别模仿2003年真题text1的第2题和第1;34题分别模仿2004年真题text1的第5 题和第3;5题模仿2002年真题text3的第5;

1. The case of Ashanthi Desilva is mentioned in the text to ____________.

[A] show the promise of gene-therapy

[B] give an example of modern treatment for fatal diseases

[C] introduce the achievement of Anderson and his team

[D] explain how gene-based treatment works

2. Andersons early success has ________________.

[A] greatly speeded the development of medicine

[B] brought no immediate progress in the research of gene-therapy

[C] promised a cure to every disease

[D] made him a national hero

3. Which of the following is true according to the text?

[A] Ashanthi needs to receive gene-therapy treatment constantly.

[B] Despite the huge funding gene researches have shown few promises.

[C] Therapeutic genes are carried by harmless viruses.

[D] Gene-doping is encouraged by world agencies to help athletes get better scores.

4. The word tarnish (line 5 paragraph 4) most probably means ____________.

[A] affect

[B] warn

[C] trouble

[D] stain

5. From the text we can see that the author seems ___________.

[A] optimistic

[B] pessimistic

[C] troubled

[D] uncertain

答案:A B C D A

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下面小编为大家准备了 研究生入学 的相关考题,供大家学习参考。

下面不属于对“学生主观能动性”描述的是(  )

A.学生具有自觉性
B.学生具有独立性
C.学生具有创造性
D.学生具有可塑性
答案:D
解析:
项体现学生的受动性。

简述北宋三次兴学。

答案:
解析:
【答案要点】
(1)第一次兴学:范仲淹在宋仁宗庆历四年主持的,史称“庆历兴学”。兴学内容主要有三:①令州县立学,规定应试科举的士人须在学校习业300日,方许应举。这项措施旨在避免学校流于形式,沦为单纯培训应试举人的场所,进而保障学校的正常教学秩序。②改革科举考试丸容,罢帖经和墨义,着重策论和经学。③振兴太学,将胡瑗的“苏湖教学法”引进太学,创立分科教学和学科的必修、选修制度,体现对当时教育空疏、流于形式的批判。庆历新政实施不过一年多,便在旧官僚权贵集团的强烈反对下失败,兴学也告夭折。但毕竟促成了宋代学校教育的兴起,一些改革措施对后世也有重大影响。
(2)第二次兴学:王安石在宋神宗熙宁年间主持的,史称“熙宁兴学”。其具体内容主要包括以下几个方面:①改革太学,创立“三舍法”。②扩建和整顿地方官学。一是设置学官全权负责管理当地教育,地方当局不得随意干预学校事务。朝廷还为地方学校拨充学田,从而在物质条件上为州县学校的维持提供了保障。③恢复与创立武学、律学、医学等专门学校,以培养具有一技之长的人才。④编撰《三经新义》,作为统一教材。为了统一经学,熙宁六年设经义局,王安石亲自修撰《诗》、《书》、《周礼》三经义。由朝廷正式颁行,成为官方考试、讲经所依据的标准教材。
(3)第三次兴学:蔡京在宋徽宗崇宁年间主持的,史称“崇宁兴学”。内容主要包括以下几个方面:①全国普遍设立地方学校。至此,形成了遍布全国州县的学校网络,无论在数量上、规模上,还是在分布的范围上,都远远地超过了以往任何一次兴学。②建立县、州、太学三级相联系的学制系统。县学考生考试升州学,州学学生再根据成绩升入太学的不同舍,成绩上者升上舍,中者升下等上舍,下者升内舍,其余升外舍。③扩建太学。④罢科举,改由学校取士。

就国家对法的作用来说,能影响以至决定法的形式的最主要的因素是(  )。
A.国家所赖以存在的经济基础
B.国家管理形式和结构形式
C.国家的中心任务
D.国家职能

答案:B
解析:
【精解】法的形式和法律制度直接受国家形式的影响。国家管理形式即政体对法有直接的影响。不同政体往往有不同的法的表现形式。在法的形式方面,单一制国家一般不存在多种法的体系,因而法的形式也不复杂。但联邦制国家有联邦法的体系和联邦各组成部分法的体系。

下列哪项与原核生物DNA复制错误率低的原因有关?
A. DNA-pol I具有3—5外切酶活性 B. DNA-pol 1具有5—3外切酶活性
C. DNA-pol III具有3—5外切酶活性 D. DNA-pol I和IIl都具有3—5外切酶活性

答案:A
解析:
酸外切酶活性是指能水解位于核酸分子链末端核苷酸的能力。因为DNA合成方向是5—3,因此3—5核酸外切酶活性与DNA合成的校对功能有关。由于DNA-pol I具有核酸外切 酶活性,能对复制中的错误进行校读、修复和填补,故复制的错误率较低[1/(109 ~1010))]。RNA-pol和 逆转录酶无3—5核酸外切酶活性,故合成错误率较高(1/106)。虽然dna-poi I、II、III均具有3— 5核酸外切酶活性,但DNA-pol II主要参与DNA损伤的应急修复,DNA-pd BI主要在复制延长中起催化 作用,故最佳答案为A,而不是C和D。

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